14,199 research outputs found

    Performance Analysis of a Dual-Hop Cooperative Relay Network with Co-Channel Interference

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    This paper analyzes the performance of a dual-hop amplify-and-forward (AF) cooperative relay network in the presence of direct link between the source and destination and multiple co-channel interferences (CCIs) at the relay. Specifically, we derive the new analytical expressions for the moment generating function (MGF) of the output signal-to-interference-plus-noise ratio (SINR) and the average symbol error rate (ASER) of the relay network. Computer simulations are given to confirm the validity of the analytical results and show the effects of direct link and interference on the considered AF relay network

    Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus

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    Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the hippocampus. We have used an immunocytochemical method to visualize and quantify the pattern of autophosphorylation of CaMKII in hippocampal slices after tetanization of the Schaffer collateral pathway. Thirty minutes after tetanic stimulation, autophosphorylated CaM kinase II (P-CaMKII) is significantly increased in area CA1 both in apical dendrites and in pyramidal cell somas. In apical dendrites, this increase is accompanied by an equally significant increase in staining for nonphosphorylated CaM kinase II. Thus, the increase in P-CaMKII appears to be secondary to an increase in the total amount of CaMKII. In neuronal somas, however, the increase in P-CaMKII is not accompanied by an increase in the total amount of CaMKII. We suggest that tetanic stimulation of the Schaffer collateral pathway may induce new synthesis of CaMKII molecules in the apical dendrites, which contain mRNA encoding its alpha-subunit. In neuronal somas, however, tetanic stimulation appears to result in long-lasting increases in P-CaMKII independent of an increase in the total amount of CaMKII. Our findings are consistent with a role for autophosphorylation of CaMKII in the induction and/or maintenance of long-term potentiation, but they indicate that the effects of tetanus on the kinase and its activity are not confined to synapses and may involve induction of new synthesis of kinase in dendrites as well as increases in the level of autophosphorylated kinase

    Moduli Stabilization and Supersymmetry Breaking in Deflected Mirage Mediation

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    We present a model of supersymmetry breaking in which the contributions from gravity/modulus, anomaly, and gauge mediation are all comparable. We term this scenario "deflected mirage mediation," which is a generalization of the KKLT-motivated mirage mediation scenario to include gauge mediated contributions. These contributions deflect the gaugino mass unification scale and alter the pattern of soft parameters at low energies. In some cases, this results in a gluino LSP and light stops; in other regions of parameter space, the LSP can be a well-tempered neutralino. We demonstrate explicitly that competitive gauge-mediated terms can naturally appear within phenomenological models based on the KKLT setup by addressing the stabilization of the gauge singlet field which is responsible for the masses of the messenger fields. For viable stabilization mechanisms, the relation between the gauge and anomaly contributions is identical in most cases to that of deflected anomaly mediation, despite the presence of the Kahler modulus. Turning to TeV scale phenomenology, we analyze the renormalization group evolution of the supersymmetry breaking terms and the resulting low energy mass spectra. The approach sets the stage for studies of such mixed scenarios of supersymmetry breaking at the LHC.Comment: 33 pages, 8 figures. Published version in Journal of High Energy Physic

    SISSO: a compressed-sensing method for identifying the best low-dimensional descriptor in an immensity of offered candidates

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    The lack of reliable methods for identifying descriptors - the sets of parameters capturing the underlying mechanisms of a materials property - is one of the key factors hindering efficient materials development. Here, we propose a systematic approach for discovering descriptors for materials properties, within the framework of compressed-sensing based dimensionality reduction. SISSO (sure independence screening and sparsifying operator) tackles immense and correlated features spaces, and converges to the optimal solution from a combination of features relevant to the materials' property of interest. In addition, SISSO gives stable results also with small training sets. The methodology is benchmarked with the quantitative prediction of the ground-state enthalpies of octet binary materials (using ab initio data) and applied to the showcase example of predicting the metal/insulator classification of binaries (with experimental data). Accurate, predictive models are found in both cases. For the metal-insulator classification model, the predictive capability are tested beyond the training data: It rediscovers the available pressure-induced insulator->metal transitions and it allows for the prediction of yet unknown transition candidates, ripe for experimental validation. As a step forward with respect to previous model-identification methods, SISSO can become an effective tool for automatic materials development.Comment: 11 pages, 5 figures, in press in Phys. Rev. Material

    Tetanic Stimulation Leads to Increased Accumulation of Ca^(2+)/Calmodulin-Dependent Protein Kinase II via Dendritic Protein Synthesis in Hippocampal Neurons

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    mRNA for the ɑ-subunit of CaMKII is abundant in dendrites of neurons in the forebrain (Steward, 1997). Here we show that tetanic stimulation of the Schaffer collateral pathway causes an increase in the concentration of ɑ-CaMKII in the dendrites of postsynaptic neurons. The increase is blocked by anisomycin and is detected by both quantitative immunoblot and semiquantitative immunocytochemistry. The increase in dendritic ɑ-CaMKII can be measured 100-200 Āµm away from the neuronal cell bodies as early as 5 min after a tetanus. Transport mechanisms for macromolecules from neuronal cell bodies are not fast enough to account for this rapid increase in distal portions of the dendrites. Therefore, we conclude that dendritic protein synthesis must produce a portion of the newly accumulated CaMKII. The increase in concentration of dendritic CaMKII after tetanus, together with the previously demonstrated increase in autophosphorylated CaMKII (Ouyang et al., 1997), will produce a prolonged increase in steady-state kinase activity in the dendrites, potentially influencing mechanisms of synaptic plasticity that are controlled through phosphorylation by CaMKII

    Mesons and Flavor on the Conifold

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    We explore the addition of fundamental matter to the Klebanov-Witten field theory. We add probe D7-branes to the N=1{\cal N}=1 theory obtained from placing D3-branes at the tip of the conifold and compute the meson spectrum for the scalar mesons. In the UV limit of massless quarks we find the exact dimensions of the associated operators, which exhibit a simple scaling in the large-charge limit. For the case of massive quarks we compute the spectrum of scalar mesons numerically.Comment: 19 pages, 3 figures, v2: typos fixe

    Electron properties of carbon nanotubes in a periodic potential

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    A periodic potential applied to a nanotube is shown to lock electrons into incompressible states that can form a devil's staircase. Electron interactions result in spectral gaps when the electron density (relative to a half-filled Carbon pi-band) is a rational number per potential period, in contrast to the single-particle case where only the integer-density gaps are allowed. When electrons are weakly bound to the potential, incompressible states arise due to Bragg diffraction in the Luttinger liquid. Charge gaps are enhanced due to quantum fluctuations, whereas neutral excitations are governed by an effective SU(4)~O(6) Gross-Neveu Lagrangian. In the opposite limit of the tightly bound electrons, effects of exchange are unimportant, and the system behaves as a single fermion mode that represents a Wigner crystal pinned by the external potential, with the gaps dominated by the Coulomb repulsion. The phase diagram is drawn using the effective spinless Dirac Hamiltonian derived in this limit. Incompressible states can be detected in the adiabatic transport setup realized by a slowly moving potential wave, with electron interactions providing the possibility of pumping of a fraction of an electron per cycle (equivalently, in pumping at a fraction of the base frequency).Comment: 21 pgs, 8 fig
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